PredictingMacro- andMicrovascular Complications in Type 2 Diabetes The Japan Diabetes Complications Study/the Japanese Elderly Diabetes Intervention Trial risk engine
نویسندگان
چکیده
RESEARCHDESIGNANDMETHODSdWe analyzed pooled data from two clinical trials on 1,748 Japanese type 2 diabetic patients without diabetes complications other than mild diabetic retinopathy with a median follow-up of 7.2 years. End points were coronary heart disease (CHD), stroke, noncardiovascular mortality, overt nephropathy defined by persistent proteinuria, and progression of retinopathy. We fit a multistate Cox regression model to derive an algorithm for prediction. The predictive accuracy of the calculated 5-year risks was cross-validated.
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